In 2017, M. LeBlanc opened in Chicago's Logan Square neighborhood, presenting an exhibition program of international contemporary art, initially drawing predominantly from artists working in: Cologne, Germany; Berlin, Germany; Los Angeles, California; and Chicago, Illinois. Berlin artist Hans-Jörg Mayer (b. 1955 in Singen, Germany) mounted the gallery’s first solo exhibition, "Kristen Stewart." The annual exhibition program is hosted by the gallery's turn-of-the-century storefront and weighted toward solo exhibitions and projects by gallery artists. This program is punctuated occasionally with young group exhibitions, readings and screenings. In 2020, M. LeBlanc began publishing artists' books and writing as well as its own exhibition catalogs.